• Prohibition was a leap into the unknown. It has failed on its own terms and caused a litany of dangers we now know all too well.
• We already regulate many risky activities and substances. For medical purposes, we produce and provide many otherwise restricted drugs (opiates as morphine, amphetamine as Adderall and Cannabis as CBD oil, etc.), without the violence and corruption that characterise the illegal trade.
• Many countries have undertaken successful reforms: Canada and Uruguay have fully legalised and regulated cannabis. Some US states have legalised, and regulated cannabis and other states have decriminalised cannabis. Portugal successfully decriminalised all drugs in 2001. Switzerland has been providing heroin-assisted therapy (HAT) programs since 1994. 
• We can also draw lessons from the regulation of other legal but risky activities, such as vaping.
• Policy changes will be carefully weighed and debated, before incremental introduction and on-going monitoring, subject to revision. We are arguing for an approach that is responsive to evidence.